Exploring Hyaluronic Acid as a Potential Standard Dressing for Burn Wound

نویسندگان

چکیده

A massive loss of dermis layer such as in deep burn wounds brings several important consequences and complications which contribute to major problems, personally economically, for the patients their families. Ideal wound treatment should not focus merely on removing devitalized tissue, controlling bacterial growth, promoting healing, but also accelerating healing process preventing scar-related complications. The evolution biomaterial science has provided physicians with novel dressing materials based natural synthetic polymers, latest development introduces use hyaluronic acid (HA) a potential dressing. HA been studied have involvement many phases process, inflammation, granulation, re-epithelialization. Dealing unfavorable physical properties native polymer solubility rapid degradation, modification improvement are designed produce insoluble molecules facilitate acid-based (HA-based) products valuable option burns. Our literature review shares outcome these currently available clinical experience suggests that HA-based provide safe therapeutic method useful acute burns minimize complications, although further improvements still required make an ideal product standard treatment.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Synthesis and evaluation of nanohydrogel film containing polyvinyl alcohol/hyaluronic acid/zinc oxide for wound dressing

Background and Aim: Lesions of the skin can impair its vital function to protect humans against external pathogens. Therefore, producing a suitable wound dressing to repair injuries is always one of the challenges of researchers. The present study aims to Synthesize a hydrogel film for wound dressing applications. Methods: In this research, a hydrogel film of polyvinyl alcohol / hyaluronic a...

متن کامل

Gelam (Melaleuca spp.) Honey-Based Hydrogel as Burn Wound Dressing

A novel cross-linked honey hydrogel dressing was developed by incorporating Malaysian honey into hydrogel dressing formulation, cross-linked and sterilized using electron beam irradiation (25 kGy). In this study, the physical properties of the prepared honey hydrogel and its wound healing efficacy on deep partial thickness burn wounds in rats were assessed. Skin samples were taken at 7, 14, 21,...

متن کامل

Production of Wound Dressing with Nano Fibers contain Bassorin/Ofloxacin for Improvement Burn Wound

Gum Tragacanth (GT) obtained from Astragalus Gossypinus is one of the most widely used natural gums which has found applications in many areas because of its attractive features such as biodegradability, nontoxic nature, natural availability, moisture absorption and creating a network of Hydrocolloid. It also has maintenance and delivery of drugs, higher resistance to microbial attacks and long...

متن کامل

Hyaluronic acid: evaluation as a potential delivery vehicle for vitronectin:growth factor complexes in wound healing applications.

We have previously reported that novel vitronectin:growth factor (VN:GF) complexes significantly increase re-epithelialization in a porcine deep dermal partial-thickness burn model. However, the potential exists to further enhance the healing response through combination with an appropriate delivery vehicle which facilitates sustained local release and reduced doses of VN:GF complexes. Hyaluron...

متن کامل

New Composites Collagen – Polyphenols as Potential Dressing for Wound Care

The aim of this study was to obtain new composites collagen-polyphenols and to investigate them as potential materials for wound dressings. Extracts from three plants: Arnica montana L., Artemisia absinthium L., and Urtica dioica L. were mixed in two different ratios and evaluated for their polyphenolic content and antioxidant activity. The herbal formulations were mixed with collagen type I an...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: International journal of medical science and clinical research studies

سال: 2022

ISSN: ['2767-8326', '2767-8342']

DOI: https://doi.org/10.47191/ijmscrs/v2-i8-13